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Lactate-lactylation in tumor angiogenesis and progression: mechanisms, biomarker potential, and therapeutic implications | Synapse
March 3, 2026
Open Access
Lactate-lactylation in tumor angiogenesis and progression: mechanisms, biomarker potential, and therapeutic implications
PW
Peiting Wu
Central South University
JZ
Juan Zhang
Central South University
ZJ
Zhengwu Jiang
Central South University
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Puntos clave
Tumor angiogenesis is significantly influenced by lactate-lactylation mechanisms, impacting progression.
The study identifies specific biomarkers linked to lactate-lactylation involvement in angiogenesis.
Observational analysis highlights potential therapeutic implications of targeting lactate-lactylation pathways.
Understanding these mechanisms may enable innovative treatment strategies and improve patient outcomes.
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Wu et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75b76c6e9836116a22cd2
https://doi.org/https://doi.org/10.1186/s40364-026-00898-z