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Magnolol inhibits the resistance of ESBLs E. coli to fourth-generation cephalosporins in vitro and in vivo | Synapse
March 3, 2026
Magnolol inhibits the resistance of ESBLs E. coli to fourth-generation cephalosporins in vitro and in vivo
YT
Yin-Chao Tong
Northwest A&F University
HL
Huan Lin
Deyang Stomatological Hospital
YY
Yu‐Miao Yang
Chinese Academy of Tropical Agricultural Sciences
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Puntos clave
Magnolol demonstrates effectiveness in reducing ESBLs E. coli resistance to fourth-generation cephalosporins.
In vitro assays reveal a significant reduction in resistance levels after magnolol treatment.
The study utilizes both in vitro and in vivo methods to validate magnolol's efficacy against resistant strains.
This finding suggests magnolol could serve as a promising adjuvant in treating resistant bacterial infections.
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Tong et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75bdbc6e9836116a23ecf
https://doi.org/https://doi.org/10.1016/j.phymed.2026.157889