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Systematic design of polybasic nanogels: influence of hydrophobic monomers on tunable physicochemical and biological properties | Synapse
March 3, 2026
Open Access
Systematic design of polybasic nanogels: influence of hydrophobic monomers on tunable physicochemical and biological properties
AW
Angela M. Wagner
The University of Texas at Austin
ID
Ishaan Duggal
Austin College
AL
Alice Lawrence
Bangor University
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Puntos clave
Enhanced biological properties observed, indicating significant design implications for nanogels.
Hydrophobic monomers were shown to tune physicochemical properties significantly, affecting gel stability and functionality.
Systematic design approach enabled the creation of polybasic nanogels with adjustable characteristics for diverse applications.
Findings highlight potential for tailored drug delivery systems, necessitating further exploration in clinical settings.
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Wagner et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75d4ec6e9836116a271a3
https://doi.org/https://doi.org/10.1038/s44385-025-00058-2