Tranexamic Acid for Melasma Treatment: An Updated Systematic Review and Meta-analysis of Randomized Controlled Trials

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• Melasma treatment with tranexamic acid shows a significant reduction in pigmentation.
• The meta-analysis reports an overall effect size of 1.54, suggesting strong treatment efficacy.
• This systematic review includes data from randomized controlled trials examining tranexamic acid use.
• Findings highlight the potential of tranexamic acid as an effective melasma therapy option.