Metabolic perturbations associated with per- and polyfluoroalkyl substances and their relationships with glycated hemoglobin in the Dutch PIAMA birth cohort | Synapse
March 3, 2026Open Access
Metabolic perturbations associated with per- and polyfluoroalkyl substances and their relationships with glycated hemoglobin in the Dutch PIAMA birth cohort
Puntos clave
Glycated hemoglobin levels increase in children exposed to per- and polyfluoroalkyl substances (PFAS), indicating metabolic disturbances.
Children with higher PFAS exposure show a significant average increase in glycated hemoglobin of 0.5%, potentially influencing long-term health outcomes.
Observational analysis within the Dutch PIAMA birth cohort highlights the relationship between PFAS exposure and metabolic perturbations.
Findings underscore the need for further investigation into PFAS exposure and metabolic health in vulnerable populations.