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Cerebral cavernous malformations in pregnancy: A systematic review of case reports and case series of hemorrhagic risk and outcomes | Synapse
March 3, 2026
Open Access
Cerebral cavernous malformations in pregnancy: A systematic review of case reports and case series of hemorrhagic risk and outcomes
MP
Matteo Palermo
Università Cattolica del Sacro Cuore
AA
Alessio Albanese
Università Cattolica del Sacro Cuore
FD
Francesco Doglietto
Università Cattolica del Sacro Cuore
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Puntos clave
Pregnancy is associated with substantial hemorrhagic risk in individuals with cerebral cavernous malformations.
A review of 25 cases indicates a notable hemorrhage rate of 36% during pregnancy.
Observational analysis of case reports and case series highlights the varied outcomes of these malformations.
Findings suggest close monitoring of pregnant individuals with cerebral cavernous malformations to mitigate risks.
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Palermo et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75ecfc6e9836116a29be3
https://doi.org/https://doi.org/10.1007/s10143-026-04136-w