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Asymmetric division in a two-cell-like state rejuvenates embryonic stem cells | Synapse
March 3, 2026
Open Access
Asymmetric division in a two-cell-like state rejuvenates embryonic stem cells
XW
Xinyi Wang
Shanghai University of Engineering Science
HF
Hong Fu
ShanghaiTech University
QS
Qingyang Sun
Shanghai Medical College of Fudan University
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Puntos clave
Asymmetric division leads to rejuvenation of embryonic stem cells, enhancing their developmental potential and functionality.
Embryonic stem cells exhibit characteristics of a two-cell-like state, indicating a key transition in cell fate determination.
Observational analysis explores mechanisms of cellular rejuvenation using advanced imaging and genetic techniques, focusing on developmental pathways.
This discovery highlights potential therapeutic approaches for regenerative medicine and understanding early development.
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Cite This Study
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Wang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75ff3c6e9836116a2c516
https://doi.org/https://doi.org/10.1038/s41422-026-01221-z