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March 3, 2026
Open Access
A microfluidic spray drying approach for developing lipid nanoparticles dry powder via anti-solvent precipitation
YZ
Yipiao Zhang
Shanghai Innovative Research Center of Traditional Chinese Medicine
YL
Yang Liu
University of Science and Technology of China
ZY
Zhu Yang
Central South University
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Puntos clave
Dry powder lipid nanoparticles were successfully developed using a microfluidic spray drying technique, enabling more efficient delivery systems.
The technique utilizes anti-solvent precipitation, which enhanced nanoparticle stability and size distribution compared to traditional methods.
Microfluidics allows precise control over formulation parameters, leading to optimized lipid nanoparticle characteristics.
This innovative approach may improve drug delivery in therapeutic applications, warranting further investigations into performance.
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A microfluidic spray drying approach for developing lipid nanoparticles dry powder via anti-solvent precipitation | Synapse
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Zhang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a7609bc6e9836116a2d85d
https://doi.org/https://doi.org/10.1016/j.ceja.2026.101073