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March 19, 2026PLOS Global Public Health0 citationsOpen Access

Sociodemographic predictors of health-related quality of life dimensions in hypertensive patients: A cross-sectional study in a Ghanaian Municipal Hospital

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GDGodfred DarkoAAAmidu AlhassanAAAlfred Akorli

Key Result

Younger age (18-35 years) strongly predicted good physical (AOR 18.97) and social quality of life (AOR 29.10) in hypertensive adults, while low income reduced quality of life across all domains.

Key Points

  • This study aims to explore how sociodemographic characteristics affect health-related quality of life in hypertensive adults.
  • Cross-sectional analytical design
  • Sample of 330 hypertensive adults from outpatient registry
  • Assessment of QoL using standardized instruments
  • Statistical analyses included Kruskal-Wallis and Mann-Whitney U tests, and logistic regression
  • Younger age, male sex, higher education, employment, higher income, and urban residence are linked to higher QoL scores.
  • Participants aged 18–35 years show significantly higher odds of good physical and social QoL.
  • Male sex is associated with better physical and psychological QoL.
  • Low income decreases the likelihood of good QoL across all domains.
  • Urban residence increases the odds of good physical QoL.

Structured PICO

P
Population
Adults with hypertension attending Mampong Ashanti Municipal Hospital
O
Outcome
Health-related quality of life (QoL) across physical, psychological, social, and environmental domainspatient reported

Sociodemographic factors including age, sex, income, and place of residence strongly influence quality of life among adults with hypertension, highlighting the need to prioritize vulnerable groups such as older, low-income, and rural patients.

Abstract

Hypertension is a major public health concern worldwide and can adversely affect multiple aspects of quality of life (QoL). Sociodemographic factors may influence how adults experience QoL, yet evidence from Ghana remains limited. This study examined the relationship between sociodemographic characteristics and QoL across physical, psychological, social, and environmental domains among adults with hypertension attending Mampong Ashanti Municipal Hospital. A cross-sectional analytical design was employed among 330 hypertensive adults, using a simple random sampling technique from the outpatient registry. QoL was assessed using standardized instruments, while sociodemographic variables included age, sex, marital status, education, employment, income, religion, and place of residence. Kruskal-Wallis and Mann-Whitney U tests explored differences in QoL scores, while logistic regression estimated crude and adjusted odds ratios (AORs) for predictors of good QoL in each domain. Data from 330 participants were analyzed; younger age, male sex, higher education, employment, higher income, and urban residence were associated with higher QoL scores. Adjusted analyses indicated that participants aged 18–35 years had higher odds of good physical (AOR = 18.97, 95% CI: 5.50-65.39) and social QoL (AOR = 29.10, 95% CI: 6.20-136.50). Male sex predicted better physical (AOR = 2.31, 95% CI: 1.20-4.44) and psychological QoL (AOR = 2.85, 95% CI: 1.54-5.26). Low income (<999 GHS) reduced the likelihood of good QoL across all domains. Urban residence increased the odds of good physical QoL (AOR = 3.18, 95% CI: 1.69-5.97). Sociodemographic characteristics; age, sex, income, and place of residence, strongly influence QoL among adults with hypertension. Interventions to improve quality of life should prioritize older adults, who report lower physical and social well-being; low-income earners, who have reduced scores across all domains, and rural residents who experience poorer physical, psychological, and social QoL.

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Cite This Study

Darko et al. (2026) studied this question. Younger age (18-35 years) strongly predicted good physical (AOR 18.97) and social quality of life (AOR 29.10) in hypertensive adults, while low income reduced quality of life across all domains.

synapsesocial.com/papers/69bb92be496e729e629804fahttps://doi.org/10.1371/journal.pgph.0006140
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