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July 10, 1981Science

Sympathetic and parasympathetic nervous activity make frequency-specific contributions to the heart rate power spectrum, and renin-angiotensin system activity strongly modulates the amplitude of the spectral peak located at 0.04 hertz.

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Authors

SAS. AkselrodDGDavid GordonFUF. Andrew Ubel

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Overview

May refine heart rate variability interpretation in research; leaves open clinical translation for autonomic assessment.

Structured PICO

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Outcome
Frequency-specific contributions to the heart rate power spectrumsurrogate

Power spectrum analysis of heart rate fluctuations reveals that the renin-angiotensin system plays a significant role in short-term cardiovascular control on the time scale of seconds to minutes.

Cite This Study

Akselrod et al. (1981) studied this question.

synapsesocial.com/papers/69d84d8ed2f7327e70ae2df9https://doi.org/10.1126/science.6166045
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Inhibition by angiotensin II of baroreceptor‐evoked activity in cardiac vagal efferent nerves in the dog.1979 · 199 citations
  2. 2Analysis of Heart Rate Variability1973 · 949 citations