Targeting the Hedgehog Signaling Pathway in the Retina Using Quercetin-Loaded Lipid Nanoparticles for Myopia Control | Synapse
April 10, 2026Open Access
Targeting the Hedgehog Signaling Pathway in the Retina Using Quercetin-Loaded Lipid Nanoparticles for Myopia Control
Puntos clave
The aim is to explore the effectiveness of quercetin-loaded lipid nanoparticles in targeting the hedgehog signaling pathway for myopia control in the retina.
Utilized quercetin-loaded lipid nanoparticles (QLSs) for retinal application.
Evaluated aqueous solubility and bioavailability of QLSs.
Assessed dose-response efficacy for myopia control.
QLSs showed excellent aqueous solubility.
Significant efficacy observed with low-dose administration.
Promising implications for clinical applications in myopia treatment.
Resumen
QLSs exhibited excellent aqueous solubility and bioavailability, enabling low-dose administration with significant efficacy, thereby presenting great prospects for clinical application.