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The validity of network meta-analysis is based on the underlying assumption that there is no imbalance in the distribution of effect modifiers across the different types of direct treatment comparisons, regardless of the structure of the evidence network.
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Jansen et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d9dfb8a1d151c65f6855a8 — DOI: https://doi.org/10.1186/1741-7015-11-159
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
Jeroen P. Jansen
Huseyin Naci
BMC Medicine
Tufts University
London School of Economics and Political Science
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