What question did this study set out to answer?

This research aims to evaluate the effectiveness of stereotactic radiosurgery (SRS) on local control outcomes in patients with brain metastases from small cell lung cancer.

April 15, 2026

Local Control Outcomes of Patients With Brain Metastases From Small Cell Lung Cancer Treated With Stereotactic Radiosurgery

Puntos clave

This research aims to evaluate the effectiveness of stereotactic radiosurgery (SRS) on local control outcomes in patients with brain metastases from small cell lung cancer.
Analyzed local control (LC) outcomes in patients treated with SRS for brain metastases.
Considered prior treatments like prophylactic cranial irradiation (PCI) and whole-brain radiotherapy (WBRT).
Recommended prescription dose ≥20 Gy or staged SRS when applicable.
SRS demonstrated high local control rates for small cell lung cancer brain metastases.
Overall survival (OS) was limited due to systemic disease progression.
The study indicates that higher doses or staged SRS may enhance treatment outcomes.

Resumen

SRS provides high LC for SCLC BM, including post-PCI/WBRT recurrences. OS remains limited by systemic progression. Prescription dose ≥20 Gy or staged SRS should be considered when feasible.

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Discussion

Authors

Anirudh Bommireddy

L. Angelov

John H. Suh

Journals

American Journal of Clinical Oncology

Actions

Institutions

Cleveland Clinic

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Local Control Outcomes of Patients With Brain Metastases From Small Cell Lung Cancer Treated With Stereotactic Radiosurgery

Puntos clave

Resumen

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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