In this economic evaluation, thymectomy was found to be a highly cost-effective intervention for nonthymomatous MG in the UK and likely to be cost-saving relative to prednisolone alone. These findings support current clinical guidelines recommending thymectomy for eligible patients and establish it as the most relevant comparator in evaluations of future health technologies. More broadly, this study demonstrates the importance of high-quality randomized clinical trial evidence in enabling health technology assessment of surgical procedures.
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Jenny Lord
Matthew Walton
Peter J. Murphy
JAMA Network Open
University of Pennsylvania
University of Sheffield
University of Alabama at Birmingham
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Lord et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69df2c77e4eeef8a2a6b19ff — DOI: https://doi.org/10.1001/jamanetworkopen.2026.6612
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