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May 7, 2026Therapeutics and Clinical Risk Management1 citationsOpen Access

Emergent ABO-Incompatible Liver Transplantation: Outcomes and Challenges

Outcome of Emergent ABO-Incompatible Liver Transplantation is Acceptable but at the Cost of Higher Diffuse Intrahepatic Biliary Stricture: A Single-Center, Retrospective Study

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Authors

JLJunfang LiuJQJiameng QiYCYing Chen

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Overview

Retrospective study finds lower survival rates in emergent ABO-incompatible liver transplantation, suggesting strategies are needed to reduce complications.

Key Points

  • This study aimed to characterize the outcomes of emergent ABO-incompatible liver transplantation and identify predictors of survival.
  • Analyzed a cohort of 110 ABO-incompatible liver transplant recipients with rituximab-based desensitization.
  • Followed up recipients for survival rates at 1, 3, and 5 years.
  • Conducted propensity score matching with a control group of 110 ABO-compatible recipients.
  • 1-year survival rate: ABO-I group 74.0% vs ABO-C group 88.0% (P = 0.024).
  • 3-year survival rate: ABO-I group 68.5% vs ABO-C group 83.0% (P = 0.024).
  • Identified risk factors for survival including age > 65 years, liver cancer prior to transplant, and incidence of diffuse intrahepatic biliary stricture.
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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69fc2c1f8b49bacb8b347b2fhttps://doi.org/10.2147/tcrm.s567879
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