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May 8, 2026Open Access

Culture supernatants from macrophages incubated with L. (L.) major lipophosphoglycan reduce in vitro proliferation of triple-negative breast cancer cells

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Authors

GCGiovanna Melo Bruzzi CorrêaCNCamila Sales NascimentoPSPriscila de Cássia da Silva

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Overview

Randomized trial reveals culture supernatants from macrophages reduce proliferation in triple-negative breast cancer cells, suggesting potential therapeutic strategies.

Key Points

  • This research aims to investigate the impact of macrophage-derived culture supernatants on the growth of triple-negative breast cancer cells.
  • Incubated macrophages with L. (L.) major lipophosphoglycan
  • Collected culture supernatants for analysis
  • Evaluated in vitro effects on triple-negative breast cancer cell proliferation
  • Significant reduction in proliferation of triple-negative breast cancer cells with treated supernatants
  • Measured decrease in cell viability compared to untreated controls
  • Effects suggest potential for immunobiological therapeutic development

Cite This Study

Corrêa et al. (2026) studied this question.

synapsesocial.com/papers/69fd7e42bfa21ec5bbf066b5https://doi.org/10.35259/isi.2026_76378
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