PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
August 22, 2025British Journal of Haematology0 citationsOpen Access

When is it time to bid farewell to anticoagulation?

View Full Paper
JCJulia CzuprynskaRARoopen Arya

Key Points

  • Deprescribing antithrombotic therapy in cancer patients is uncommon, leading to potential risks.
  • The study reported on outcomes associated with antithrombotic therapy in patients nearing end of life.
  • Cohort study using population-linked data provides insights into prescribing behaviors in this group.
  • Enhanced awareness is needed to support better decision-making in high-risk cancer patients.

Abstract

Decisions about antithrombotic therapy in cancer patients at the end of life can be challenging. This cohort study examined prescribing behaviour and outcomes relating to antithrombotic therapy in this patient group, finding that deprescribing was uncommon. Greater awareness of this neglected but high‐risk aspect of patient care is required along with interventions to enable shared decision‐making in this setting. Commentary on: Aldridge et al. Antithrombotic therapy in patients with cancer at the end of life and associated clinical outcomes: a cohort study using population‐linked routinely collected data. Br J Haematol 2025 (Online ahead of print). https://doi.org/10.1111/bjh.70032 .

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Czuprynska et al. (2025) studied this question.

synapsesocial.com/papers/68af5231ad7bf08b1eada641https://doi.org/10.1111/bjh.70114
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Anticoagulant Use for Atrial Fibrillation Among Persons With Advanced Dementia at the End of Life2021 · 30 citations
  2. 2Prognosis of Cancers Associated with Venous Thromboembolism2000 · 1,643 citations
  3. 3Anti‐thrombotic therapy in patients with cancer at the end of life: A cohort study using population‐linked routinely collected data2025 · 7 citations
  4. 4Use of antithrombotic therapy and the risk of cardiovascular outcomes and bleeding in cancer patients at the end of life: a Danish nationwide cohort study2024 · 14 citations
  5. 5Discontinuation of Anticoagulants and Occurrence of Bleeding and Thromboembolic Events in Vitamin K Antagonist Users with a Life-Limiting Disease2025 · 9 citations