Neurodegenerative disorders like Alzheimer’s, Parkinson’s, and dementia are increasing globally due to limited long-term treatments. This review highlights the neuroprotective potential of Salvinia species, aquatic ferns rich in bioactive compounds such as flavonoids, alkaloids, and phenolics. These phytochemicals exhibit antioxidant, anti-inflammatory, neurotransmitter-modulating, and mitochondrialprotective activities. The review critically examines their role in targeting key pathological features like β-amyloid accumulation, tau destabilization, and dopaminergic neuron loss. While in vitro and in vivo results are promising, further pharmacological and clinical studies are essential to validate Salvinia as a potential source of therapeutic agents for cognitive disorders.
Chaudhari et al. (2025) studied this question.