PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
January 17, 2018New England Journal of Medicine1,427 citationsOpen Access

Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer

View Full Paper
WDWillemien J. van DrielSKSimone N. KooleKSKarolina Sikorska

Key Points

Key points are not available for this paper at this time.

Abstract

Among patients with stage III epithelial ovarian cancer, the addition of HIPEC to interval cytoreductive surgery resulted in longer recurrence-free survival and overall survival than surgery alone and did not result in higher rates of side effects. (Funded by the Dutch Cancer Society; ClinicalTrials.gov number, NCT00426257 ; EudraCT number, 2006-003466-34 .).

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Driel et al. (2018) studied this question.

synapsesocial.com/papers/69d818a2a2a48916bbbeefc9https://doi.org/10.1056/nejmoa1708618
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Population pharmacokinetics of cisplatin in patients with advanced ovarian cancer during intraperitoneal hyperthermia chemotherapy.2002 · 85 citations
  2. 2Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial2010 · 602 citations
  3. 3Thermal enhancement of drug uptake and DNA adducts as a possible mechanism for the effect of sequencing hyperthermia on cisplatin-induced cytotoxicity in L1210 cells1994 · 77 citations
  4. 4The Effect of Debulking Surgery after Induction Chemotherapy on the Prognosis in Advanced Epithelial Ovarian Cancer1995 · 724 citations
  5. 5The Role of Hyperthermic Intraperitoneal Intraoperative Chemotherapy in Ovarian Cancer2015 · 32 citations