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August 21, 2013New England Journal of Medicine2,723 citationsOpen Access

Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease

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WSWilliam J. SandbornBFBrian G. FeaganPRPaul Rutgeerts

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Abstract

Among patients with moderately to severely active Crohn's disease, those receiving intravenous ustekinumab had a significantly higher rate of response than did those receiving placebo. Subcutaneous ustekinumab maintained remission in patients who had a clinical response to induction therapy. (Funded by Janssen Research and Development; ClinicalTrials.gov numbers, NCT01369329 , NCT01369342 , and NCT01369355 .).

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Sandborn et al. (2013) studied this question.

synapsesocial.com/papers/69db2bcd5b363cdf1c835875https://doi.org/10.1056/nejmoa1215739
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