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September 19, 2022Journal of Clinical Oncology212 citationsOpen Access

Selpercatinib in Patients With RET Fusion–Positive Non–Small-Cell Lung Cancer: Updated Safety and Efficacy From the Registrational LIBRETTO-001 Phase I/II Trial

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ADAlexander DrilonVSVivek SubbiahOGOliver Gautschi

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Abstract

In a large cohort with extended follow-up, selpercatinib continued to demonstrate durable and robust responses, including intracranial activity, in previously treated and treatment-naive patients with RET fusion-positive NSCLC.

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Drilon et al. (2022) studied this question.

synapsesocial.com/papers/69dd700480eea7d3f699cd15https://doi.org/10.1200/jco.22.00393
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