What question did this study set out to answer?

This research aims to determine whether right hemicolectomy or appendectomy is more effective for treating appendiceal neuroendocrine tumors sized 1–2 cm.

April 16, 2026Journal of Neuroendocrinology

Hemicolectomy or appendectomy for appendiceal neuroendocrine tumours sized 1–2 cm? A retrospective population‐based study of 1514 patients

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Authors

KTKer Shiong Tan AAAya Abdelhameed MMMohamed Mortagy

Discussion

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Overview

Retrospective analysis reveals that appendectomy is sufficient for managing aNET in adults, suggesting improved guidelines.

Key Points

This research aims to determine whether right hemicolectomy or appendectomy is more effective for treating appendiceal neuroendocrine tumors sized 1–2 cm.
Analyzed data from SEER and NCRAS databases for patients diagnosed with aNET between 2012 and 2022.
Conducted Kaplan–Meier survival analysis and log-rank tests for overall survival.
Performed univariable and multivariable Cox regression to assess all-cause mortality.
No statistically significant difference in overall survival between appendectomy and right hemicolectomy in either cohort.
Survival rates for appendectomy are non-inferior to RHC even in node-positive disease patients.
Findings highlight a need to update clinical practice guidelines regarding the treatment of aNET.

Cite This Study

Tan et al. (2026) studied this question.

synapsesocial.com/papers/69e07cc02f7e8953b7cbdf49 https://doi.org/10.1111/jne.70179

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April 16, 2026Journal of Neuroendocrinology

Hemicolectomy or appendectomy for appendiceal neuroendocrine tumours sized 1–2 cm? A retrospective population‐based study of 1514 patients

View Full Paper

Ask AI

Bookmark

Authors

KTKer Shiong Tan AAAya Abdelhameed MMMohamed Mortagy

Discussion

Member takes

Overview

Retrospective analysis reveals that appendectomy is sufficient for managing aNET in adults, suggesting improved guidelines.

Key Points

This research aims to determine whether right hemicolectomy or appendectomy is more effective for treating appendiceal neuroendocrine tumors sized 1–2 cm.
Analyzed data from SEER and NCRAS databases for patients diagnosed with aNET between 2012 and 2022.
Conducted Kaplan–Meier survival analysis and log-rank tests for overall survival.
Performed univariable and multivariable Cox regression to assess all-cause mortality.
No statistically significant difference in overall survival between appendectomy and right hemicolectomy in either cohort.
Survival rates for appendectomy are non-inferior to RHC even in node-positive disease patients.
Findings highlight a need to update clinical practice guidelines regarding the treatment of aNET.

Cite This Study

Tan et al. (2026) studied this question.

synapsesocial.com/papers/69e07cc02f7e8953b7cbdf49 https://doi.org/10.1111/jne.70179

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