What question did this study set out to answer?

This research aims to characterize the genome of Lentzea sp. H45 and its potential for producing bioactive compounds.

April 17, 2026Open Access

Draft genome sequence of Lentzea sp. H45 from high-altitude Atacama Desert soil

Key Points

This research aims to characterize the genome of Lentzea sp. H45 and its potential for producing bioactive compounds.
Sequencing the draft genome of Lentzea sp. H45
Analyzing genome size and GC content
Identifying biosynthetic gene clusters
The genome size is 8.7 Mbp with 70.9% GC content.
Identified 34 biosynthetic gene clusters.
Contains a putative oligosaccharide cluster linked to lentzeoside biosynthesis.

Abstract

We report the draft genome sequence of Lentzea sp. H45, an extremotolerant actinobacterium from high-altitude Atacama Desert soil, producing anti-HIV-1 integrase lentzeosides. The genome comprises 8.7 Mbp with 70.9% GC content and harbors 34 biosynthetic gene clusters, including a putative oligosaccharide cluster for lentzeoside biosynthesis.

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Zhou et al. (Wed,) studied this question.

www.synapsesocial.com/papers/69e1cf985cdc762e9d8587cd — DOI: https://doi.org/10.1128/mra.01122-25

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Isolation and anti-HIV-1 integrase activity of lentzeosides A–F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude Atacama Desert soil

Authors

Wei Zhou

Jenileima Kshetrimayum Devi

Nick Allenby

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Draft genome sequence of Lentzea sp. H45 from high-altitude Atacama Desert soil

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion