We report the draft genome sequence of Lentzea sp. H45, an extremotolerant actinobacterium from high-altitude Atacama Desert soil, producing anti-HIV-1 integrase lentzeosides. The genome comprises 8.7 Mbp with 70.9% GC content and harbors 34 biosynthetic gene clusters, including a putative oligosaccharide cluster for lentzeoside biosynthesis.
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Wei Zhou
Jenileima Kshetrimayum Devi
Nick Allenby
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Zhou et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69e1cf985cdc762e9d8587cd — DOI: https://doi.org/10.1128/mra.01122-25