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September 1, 2010Heart247 citations

Inconsistent grading of aortic valve stenosis by current guidelines: haemodynamic studies in patients with apparently normal left ventricular function

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JMJan MinnersMAMartin AllgeierCGChrista Gohlke-Baerwolf

Structured PICO

P
Population
333 consecutive patients with aortic valve stenosis (echocardiography showing aortic valve area ≤2 cm² and shortening fraction ≥30%)
I
Intervention
Cardiac catheterisation for haemodynamic assessment
O
Outcome
Proportion of patients with inconsistent grading of aortic valve stenosis (aortic valve area <1 cm² and mean pressure gradient ≤40 mm Hg) on invasive testingsurrogate

Inconsistent grading of severe aortic stenosis (small valve area but low gradient) is common even on invasive cardiac catheterization and is not fully explained by low stroke volume.

Abstract

BACKGROUND: On echocardiography approximately one-third of patients with severe aortic valve stenosis based on aortic valve area (AVA or =30%. On invasive testing 85 patients (26%) demonstrated inconsistent (AVA40 mm Hg) with the remainder (28%) presenting with a calculated AVA> or =1 cm(2). Inconsistently graded patients were older (71 vs 67 years, p35 ml/m(2). CONCLUSION: In the framework of current guidelines inconsistent grading of aortic valve stenosis is common, extends to cardiac catheterisation and is only partially explained by low stroke volume despite apparently normal left ventricular systolic function.

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Cite This Study

Minners et al. (2010) studied this question.

synapsesocial.com/papers/69f69121e405cc4465bc2a71https://doi.org/10.1136/hrt.2009.181982
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