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May 8, 2026ACS Applied Materials & Interfaces0 citations

Polysaccharide-Based Soluble Microneedle Transdermal Delivery of Curcumin Synergized with Photothermal Therapy for Acne Treatment

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DKDilini Maheshika Gunarathne KannapathirageSTShuohong TangXMXueyan Ma

Key Points

  • This research aims to assess the efficacy of a polysaccharide-based microneedle system delivering curcumin combined with photothermal therapy for treating acne.
  • Developed a soluble microneedle system using polysaccharides for transdermal delivery of curcumin.
  • Evaluated the treatment's effects on skin thickness and acne symptoms in a controlled clinical setting.
  • Utilized photothermal therapy alongside microneedle application.
  • Demonstrated significant improvement in acne symptoms compared to baseline.
  • Restored skin thickness to near-normal levels after treatment.

Abstract

and restored skin thickness to near-normal levels. Collectively, this microneedle system demonstrates a highly effective and patient-friendly approach to acne vulgaris treatment.

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Cite This Study

Kannapathirage et al. (2026) studied this question.

synapsesocial.com/papers/69fd7d94bfa21ec5bbf06012https://doi.org/10.1021/acsami.6c03940
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Microneedle-Mediated Transdermal Drug Delivery for the Treatment of Multiple Skin Diseases2025
  2. 2Proteoglycan Mimetics-Based Antimicrobial and Anti-Inflammatory Microneedles Restoring Dysregulated Lipid Metabolism and Suppressing Skin Atrophy for Acne Treatment.2026
  3. 3Dissolved bubble microneedle patches for co-delivery of hydrophobic and hydrophilic drugs to improve acne vulgaris therapy2025
  4. 4Dissolved bubble microneedle patches for co-delivery of hydrophobic and hydrophilic drugs to improve acne vulgaris therapy2025
  5. 5Dissolving Hyaluronic Acid-Based Microneedles to Transdermally Deliver Eugenol Combined with Photothermal Therapy for Acne Vulgaris Treatment2024 · 23 citations