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January 18, 2026Langmuir

3D-Printed Short-Fiber Aerogel Scaffolds for Smart Drug Delivery

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Authors

KWKefeng WangJHJingtao HuYCYutong Chen

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Overview

Demonstrates a novel aerogel scaffold for controlled drug release in bone tissue engineering, suggesting improved treatment strategies.

Key Points

  • The aim is to address the challenges of drug release rates and mechanical properties in aerogel scaffolds for bone tissue engineering.
  • Designed a multifunctional smart aerogel scaffold combining electrospinning and direct ink writing technology.
  • Embedded rifampicin-loaded PLA/PCL short fibers in a composite aerogel matrix.
  • Utilized alternating magnetic field stimulation for on-demand drug release.
  • Incorporation of short fibers reduced rifampicin release rates and improved mechanical properties.
  • The scaffold maintained a localized temperature of 42 °C under magnetic stimulation, enabling accelerated drug release.
  • Provided a novel strategy for intelligent treatment of bone tuberculosis.

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/696c789ceb60fb80d1396bf7https://doi.org/10.1021/acs.langmuir.5c05782
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