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January 18, 2026Journal of Alzheimer s Disease Reports0 citationsOpen Access

Association between sensory impairment and incident dementia among middle-aged and older Chinese: Findings from the CHARLS cohort study

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QZQ ZhangCFChaofeng Fan

Key Points

  • To explore the relationship between sensory impairments and the risk of developing dementia among adults in China.
  • Analyzed data from the China Health and Retirement Longitudinal Study involving 7664 dementia-free adults aged ≥45
  • Followed participants from 2011–2012 to 2018 to track new dementia cases
  • Assessed sensory impairments based on self-reported vision and hearing abilities, defining dual sensory impairment as both vision and hearing loss
  • Used logistic regression to calculate odds ratios for dementia risk
  • 1022 participants (13.34%) developed dementia during follow-up
  • Near/distance vision impairment and hearing impairment were linked to increased dementia risk (OR for VI: 1.75 and 1.93; OR for HI: 3.02)
  • Dual sensory impairment significantly raised dementia risk (OR: 2.94)
  • Strong associations maintained among participants aged ≥60, and VI was the sole significant factor in those <60
  • Rural participants showed more pronounced sensory impairment-dementia associations

Abstract

Background Aging is accompanied by increase in sensory impairments (SIs), including vision impairment (VI), hearing impairment (HI), and dual sensory impairment (DSI). However, prospective evidence on this association from nationally representative cohorts in China remains limited. Objective To investigate the association between SIs and incident dementia among Chinese adults. Methods From the China Health and Retirement Longitudinal Study, 7664 dementia-free adults aged ≥45 at baseline (2011–2012) were followed up until 2018 to detect incident dementia. VI (near and distance) and HI were assessed based on self-reported vision and hearing capabilities. DSI was defined as having both VI and HI. Dementia was ascertained based on cognitive batteries, informant reports, and the Activity of Daily Living scale. Logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Results During the follow-up, 1022 (13.34%) participants developed dementia. Overall, near/distance VI (OR: 1.75 1.13, 2.72 / 1.93 1.29, 2.89) and HI (OR: 3.02 1.30, 7.02) were all associated with higher risk of dementia. People with DSI had a significantly higher risk of dementia compared with those without SI or with only one type of SI at baseline (OR: 2.94 1.27, 2.95). The associations between SIs/DSI and dementia remained significant among people aged≥60 years. However, only VI was associated with dementia among people aged<60 years. After stratification by residence, the SI-dementia associations were more pronounced among rural participants. Conclusions SIs are associated with a higher risk of dementia. Interventions addressing SIs should be included in dementia prevention strategies.

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Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/696c789ceb60fb80d1396cd0https://doi.org/10.1177/25424823251415174
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