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February 6, 2026Journal of Biochemicals and PhytomedicineOpen Access

Green Synthesis, Characterization, and In Vivo Anti-Plasmodial Activity of Copper Oxide Nanoparticles Using Moringa oleifera Leaf Extract

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Authors

OOOlutayo Olawumi OlajideSES. Salau EmmanuelOFOmotola Michael Fayomi

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Overview

In vivo evaluation shows CuONPMOLE exhibits significant antiplasmodial activity in malaria, suggesting effective treatment potential.

Key Points

  • This study aims to synthesize copper oxide nanoparticles using Moringa oleifera and evaluate their antiplasmodial effects.
  • Synthesize CuONPMOLE using Moringa oleifera leaf extract.
  • Characterize nanoparticles using UV-vis, FT-IR, SEM, EDX, and XRD.
  • Assess the inhibitory activity against Plasmodium berghei in rats.
  • CuONPMOLE showed a morphology that is predominantly spherical.
  • EDX analysis confirmed 85.87% presence of Cu atoms.
  • Average nanoparticle size was measured at 20.34 nm.
  • Inhibitory activity against Plasmodium berghei was 43.37 ± 2.46%, indicating significant antiplasmodial activity.

Cite This Study

Olajide et al. (2025) studied this question.

synapsesocial.com/papers/698586498f7c464f2300a551https://doi.org/10.34172/jbp.2025.5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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