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February 6, 2026European Heart Journal0 citations

What would be the impact on the burden of hypertension of achieving public health goals?

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CGC GraveLCL C Carcaillon-BentataCBChristophe Bonaldi

Key Result

Reducing daily salt intake by 40% could prevent 8% of cardio-cerebro-vascular and renal diseases, avoiding 19,494 deaths and 140,996 hospitalizations attributable to hypertension in France.

Key Points

  • The aim is to evaluate how achieving public health goals can affect hypertension-related health outcomes in France.
  • Estimated the potential impact fraction and avoidable deaths using data from the Esteban survey and a national database.
  • Assessed the effects of systolic blood pressure reductions on morbidity and mortality across four health scenarios.
  • Examined the impact of changes in salt intake, physical activity, obesity prevalence, and hypertension management.
  • A 40% reduction in salt intake could prevent 19,494 deaths and 140,996 hospitalizations.
  • A 29% increase in physical activity could prevent 3,696 deaths and 21,534 hospitalizations.
  • A 15% reduction in adult obesity could prevent 1,276 deaths and 8,188 hospitalizations.
  • A 25% reduction in uncontrolled hypertension could prevent 11,808 deaths and 77,600 hospitalizations.

Structured PICO

Does achieving public health goals for lifestyle factors and hypertension control reduce hypertension-related deaths and hospitalizations in the French population?

P
Population
A modeling study using national survey and administrative data to estimate the impact of achieving public health goals on hypertension-related morbidity and mortality in France.
E
Exposure
Modeled achievement of public health goals (Scenario 1: 40% reduction in daily salt intake; Scenario 2: 80% of adults reaching recommended physical activity; Scenario 3: 15% reduction in adult obesity prevalence; Scenario 4: 25% reduction in uncontrolled hypertension rate)
C
Comparator
Current population levels of risk factors and hypertension control
O
Outcome
Avoidable deaths and hospitalizations attributable to hypertension (cardio-cerebro-vascular and renal diseases)hard clinical

Ambitious primary prevention measures targeting salt intake, physical activity, obesity, and hypertension control could prevent tens of thousands of deaths and hospitalizations in France.

Abstract

Abstract Background High blood pressure is responsible for 55,000 deaths and 390,000 hospitalizations per year in France. Although excessive salt consumption, physical inactivity, and obesity are well-known major risk factors for hypertension, they remain highly prevalent in the general French population. Purpose The aim is to study the impact of achieving World Health Organization (WHO) or national prevention goals, in France, through primary prevention measures or improvement in the management rate of uncontrolled hypertension cases on hypertension-related morbidity and mortality. Methods The potential impact fraction (PIF) and the number of avoidable deaths and hospitalizations were estimated using blood pressure data from the Esteban survey, 2021 morbidity and mortality data from a national medicoadministrative database, and hypertension-related complication risks from the literature. The impact of systolic blood pressure (SBP) reductions and associated complications (cardio-cerebro-vascular and renal diseases) was assessed under four scenarios and was quantified at the national level: Scenario 1: Reduce the population's daily salt intake by 40%. Scenario 2: Increase physical activity so that 80% of adults reach the recommended level (75–150 min/week). Scenario 3: Reduce the prevalence of adult obesity by 15% Scenario 4: Reduce the uncontrolled hypertension rate by 25% Results Scenario 1, which would result in an average daily salt intake of 5g/day (compared to 8g currently) and an average reduction in SBP of 4,9 mmHg, could prevent 8% of cardio-cerebro-vascular and renal diseases, thereby avoiding 19,494 deaths and 140,996 hospitalizations attributable to hypertension. The 29% increase in physical activity modelled in Scenario 2 could prevent 2.0% of cardio-cerebro-vascular and renal diseases, equivalent to 3,696 deaths and 21,534 hospitalizations attributable to hypertension. Scenario 3 could prevent 0.7% of cardio-cerebro-vascular and renal diseases, corresponding to 1,276 deaths and 8,188 hospitalizations attributable to hypertension. Finally, a 25% reduction in the uncontrolled hypertension in France would prevent 7.0% of hypertension complications (11,808 deaths and 77,600 hospitalizations). Conclusion(s) The burden of hypertension could be significantly reduced by achieving national public health goals. Given the expected benefits ambitious prevention measures, targeting both primary prevention and the management of hypertension, should be implemented to reach these objectives.

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Cite This Study

Grave et al. (2025) studied Hypertension. Public health goals (salt reduction, physical activity, obesity reduction, hypertension control) vs. Current population risk factors was evaluated on Cardio-cerebro-vascular and renal diseases, deaths, and hospitalizations attributable to hypertension. Reducing daily salt intake by 40% could prevent 8% of cardio-cerebro-vascular and renal diseases, avoiding 19,494 deaths and 140,996 hospitalizations attributable to hypertension in France.

synapsesocial.com/papers/698586ad8f7c464f2300a627https://doi.org/10.1093/eurheartj/ehaf784.3423
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1NATIONWIDE IMPACT OF ADDING AN ADDITIONAL ANTIHYPERTENSIVE AGENT IN TREATED PATIENTS WITH UNCONTROLLED HYPERTENSION2026
  2. 2Burden of Cardio-Cerebrovascular and Renal Diseases Attributable to Systolic Hypertension in France in 20212024 · 16 citations
  3. 3The Global Risk Approach Should Be Better Applied in French Hypertensive Patients: A Comparison between Simulation and Observation Studies2011 · 23 citations
  4. 4Patterns of hypertension management in France in 2015: The ESTEBAN survey2020 · 87 citations
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