Retrospective analysis evaluates LDL targets in elderly high cardiovascular risk populations, indicating treatment disparities.
Key Points
The aim was to evaluate LDL-C target adherence among elderly patients at high cardiovascular risk and assess guideline adherence at the first hospital visit.
Retrospective analysis of patient data from the AGING HEART Zurich Cohort.
Included adult patients hospitalized from 2015 to 2024.
Categorized patients using ASCVD risk via ESC SCORE2 criteria.
Divided patients into age groups: ≥80 years and 65-79 years.
Primary outcome measured was guideline-directed medical treatment by LDL concentration.
3,237 patient datasets were analyzed, with 67.2% men and an average age of 76.7 years.
82.7% of patients were classified as 'very high risk' according to SCORE2 or SCORE-OP.
Statin therapy was administered to 66.7% of high-risk patients.
No significant difference in statin treatment rates between age groups (67.9% ages 65-79; 65.1% ages 80+).
Achieving LDL target of <1.4 mmol/L differed significantly between age groups (44.9% very elderly vs. 59.3% elderly; p=0.0001).