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February 14, 2026The European Journal of Contraception & Reproductive Health Care0 citations

Medical habit or necessity? Investigating misoprostol use for IUD insertion in Europe

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LELisa EggebrechtMRManuel RizzoMKMoritz Klinghardt

Key Points

  • The research aims to investigate the use of misoprostol for IUD insertion across Europe despite its lack of medical indication.
  • Conducted an observational analysis of practices across various European countries.
  • Documented the frequency of misoprostol use before IUD insertion.
  • Compared observed practices to existing medical guidelines.
  • Misoprostol was frequently used for IUD insertion, showing significant variation across countries.
  • Discrepancies were identified between common practices and established clinical guidelines.
  • The findings suggest a need for improved alignment with evidence-based care.

Abstract

Misoprostol was frequently used before IUD insertion despite lacking medical indication and showing wide variation across Europe, revealing discrepancies between practice and guidelines and highlighting the need for better alignment with evidence-based care.

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Cite This Study

Eggebrecht et al. (2026) studied this question.

synapsesocial.com/papers/699010942ccff479cfe56efchttps://doi.org/10.1080/13625187.2026.2625138
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1S2k-Guideline Non-hormonal Contraception, Part 2: Intrauterine Devices and Sterilization2024 · 2 citations
  2. 2U.S. Selected Practice Recommendations for Contraceptive Use, 20242024 · 138 citations
  3. 3Population characteristics of intrauterine device users in real-world clinical practice across Europe – insights from the EURAS-LCS12 study2025 · 2 citations
  4. 4Effect of vaginal administration of misoprostol before intrauterine contraceptive insertion following previous insertion failure: a double blind RCT2015 · 31 citations
  5. 5Self-Administered Misoprostol or Placebo Before Intrauterine Device Insertion in Nulliparous Women2012 · 52 citations