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February 14, 2026AIP AdvancesOpen Access

Rapid detection of Fusobacterium nucleatum in saliva using magnetic flux change

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Authors

SYS. YabukamiABAmane BanTMToru Murayama

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Overview

This test detects Fusobacterium nucleatum in saliva rapidly, indicating a promising method for bacterial analysis.

Key Points

  • The aim is to develop a rapid and sensitive test for detecting Fusobacterium nucleatum in saliva using magnetic flux changes.
  • Designed a low-cost antigen test employing magnetic nanoparticles.
  • Measured changes in magnetic flux due to the antigen-antibody reaction.
  • Optimized the size of a differential pickup coil for improved signal-to-noise ratio.
  • Validated the method with samples from 28 individuals.
  • Demonstrated a strong correlation with qPCR analysis (correlation coefficient = 0.69, p < 0.0001).
  • Provided low-cost and rapid evaluation of Fusobacterium nucleatum.
  • Showed high sensitivity and minimal contamination interference.

Cite This Study

Yabukami et al. (2026) studied this question.

synapsesocial.com/papers/699010ce2ccff479cfe56fd4https://doi.org/10.1063/9.0001065
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