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March 1, 2026Metabolomics0 citationsOpen Access

A plasma metabolomic fingerprint of moderate or severe hearing loss

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YLY. LiCSCatherine SchairerDWD. Bradley Welling

Key Points

  • The research aims to explore the relationship between plasma metabolomic profiles and the risk of adult-onset moderate or severe hearing loss.
  • Conducted a population-based investigation
  • Analyzed plasma metabolomic profiles
  • Identified associations between metabolites and hearing loss
  • Triglycerides showed positive associations with hearing loss
  • Steroid esters exhibited inverse associations with hearing loss
  • Metabolic perturbations may contribute to the development of hearing loss

Abstract

In this population-based investigation, we identified that triglycerides were enriched for positive associations, while steroid esters were inversely associated with adult-onset moderate or severe hearing loss. This study indicates that metabolic perturbations may contribute to the pathoetiology underlying adult-onset hearing loss.

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Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69a3d8caec16d51705d2ffeehttps://doi.org/10.1007/s11306-026-02395-8
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