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March 3, 2026Molecular Biology Reports0 citations

Genetic variants of APOE and CCR4 as determinants of myocardial infarction among type 2 diabetes patients: a South Indian case–control analysis

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PSPraveen Kumar Chandra SekarAGAshok GovindarajRVRamakrishnan Veerabathiran

Key Points

  • Myocardial infarction rates were significantly linked to APOE and CCR4 variants in type 2 diabetes patients.
  • The study identified specific genetic variants that contribute to increased risk of myocardial infarction, including those in the APOE and CCR4 genes.
  • Analysis focused on South Indian patients with type 2 diabetes, revealing novel associations between genetic variants and myocardial infarction risk.
  • Understanding these genetic influences may lead to targeted prevention strategies for myocardial infarction in type 2 diabetes individuals.
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Cite This Study

Sekar et al. (2026) studied this question.

synapsesocial.com/papers/69a75a5fc6e9836116a201b9https://doi.org/10.1007/s11033-026-11489-4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association of APOE polymorphisms with diabetes and cardiometabolic risk factors and the role of APOE genotypes in response to anti-diabetic therapy: results from the AIDHS/SDS on a South Asian population2015 · 26 citations
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  3. 3Apolipoprotein E gene polymorphisms in patients with premature myocardial infarction: a case-controlled study in Asian Indians in North India2003 · 36 citations
  4. 4Diabetes and cardiovascular disease. The Framingham study1979 · 3,995 citations
  5. 5Association of traditional cardiovascular risk factors in adults younger than 55 years with coronary heart disease. Case-control study2020 · 10 citations