This review highlights advances in programmable DNA nanostructure sensing platforms, indicating their potential in diagnostics and safety applications.
Key Points
Programmable DNA nanostructures enhance sensing platform performance, improving sensitivity and specificity.
Key advances in signal transduction mechanisms have transformed biosensing capabilities in various applications.
Reviewing multiple sensing modalities, including chemical and physical sensing, reveals design strategies and applications.
Current challenges hinder practical use of DNA nanostructures, suggesting further research directions are needed for successful implementation.