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March 3, 2026Menopause The Journal of The North American Menopause Society0 citationsOpen Access

Deciphering the predictors of endometrial nonbenign lesions in asymptomatic postmenopausal women via explainable machine learning

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LYLinlin YangCXChen XuRSRongjia Su

Key Points

  • Endometrial nonbenign lesions were accurately predicted using a machine learning model, improving diagnosis accuracy.
  • The nomogram presented significant insights, aiding clinicians in personalized treatment plans and avoiding unnecessary surgeries.
  • We utilized an LR-based nomogram model with SHAP for interpretability to analyze predictors of lesions in women.
  • This modeling may enhance clinical decision-making, highlighting the need for further validation in diverse settings.

Abstract

We developed an LR-based nomogram model and interpreted using the SHAP method, which provided visual insights for detecting endometrial nonbenign lesions in asymptomatic postmenopausal women. This approach would aid clinicians in providing individualized treatment and help avoid unnecessary invasive surgeries.

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Cite This Study

Yang et al. (2026) studied this question.

synapsesocial.com/papers/69a75b3ec6e9836116a223c4https://doi.org/10.1097/gme.0000000000002699
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