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March 3, 2026Nature Medicine35 citations

Fecal microbiota transplantation plus pembrolizumab and axitinib in metastatic renal cell carcinoma: the randomized phase 2 TACITO trial

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SPSerena PorcariCCChiara CICCARESEVHVitor Heidrich

Key Points

  • Fecal microbiota transplantation may improve responses in patients with metastatic renal cell carcinoma.
  • The overall response rate was assessed, revealing promising outcomes in treatment groups.
  • Randomized phase 2 trial design with comparative analysis of treatment efficacy and safety.
  • This study emphasizes potential synergistic effects, indicating combined therapy may enhance treatment results.
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Cite This Study

Porcari et al. (2026) studied this question.

synapsesocial.com/papers/69a75baac6e9836116a236fchttps://doi.org/10.1038/s41591-025-04189-2
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