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March 3, 2026Archives of Biological Psychiatry1 citationsOpen Access

Atypical Presentation of Glioblastoma Mimicking Dementia Symptoms

Atypical presentation of massive glioblastoma mimicking rapidly progressive dementia

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Authors

JKJatin KalitaAMApurba Narayan MahatoSSSukanto Sarkar

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Overview

Case illustrates rapid cognitive decline due to glioblastoma misdiagnosed as dementia, highlighting diagnostic challenges.

Key Points

  • Abrupt onset of paranoia and memory impairment indicated a significant underlying issue, leading to a complex diagnosis.
  • Neuroimaging ultimately revealed a massive glioblastoma, which was confirmed through histopathology post-surgery.
  • Surgical excision was performed, followed by a recommendation for radiotherapy due to the aggressive nature of the tumor.
  • Early intervention is crucial, as misdiagnosis can delay effective treatment and worsen outcomes for patients.
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Cite This Study

Kalita et al. (2026) studied this question.

synapsesocial.com/papers/69a75bbac6e9836116a2395ehttps://doi.org/10.25259/abp_12_2025
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