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March 3, 2026European Journal of Gastroenterology & Hepatology0 citations

MicroRNA hepatocellular carcinoma detect: discriminant function based on a circulating panel of microRNA for accurate diagnosis of hepatocellular carcinoma patients on top hepatitis C virus infection

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HSH. SalehHEHatem A. El-mezayenAEAml M. El-sharkawy

Key Points

  • Detection rates for HCC are improved using the miR-HCC Detect score, which surpasses individual biomarker performance.
  • The analysis shows that circulating miRNAs serve as effective noninvasive biomarkers for hepatocellular carcinoma.
  • Assessment shows that hepatitis C virus infection status influences the diagnostic accuracy of the microRNA panel.
  • This study highlights the need for further validation of noninvasive diagnostic tools for early HCC detection.

Abstract

These circulating miRNAs represent promising noninvasive biomarkers for HCC detection in HCV-infected patients. The miR-HCC Detect score outperforms individual miRNAs and may improve early HCC surveillance.

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Cite This Study

Saleh et al. (2026) studied this question.

synapsesocial.com/papers/69a75c6ec6e9836116a2553bhttps://doi.org/10.1097/meg.0000000000003145
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