Serum and cerebral folate are normal in Down Syndrome Regression Disorder

Key Points

• Serum and cerebral folate levels were found to be normal in individuals diagnosed with Down Syndrome Regression Disorder.
• The findings indicate the absence of folate deficiency as a causative factor in regression symptoms, supporting the current understanding of the disorder.
• This observational analysis suggests that other mechanisms may be implicated in the symptoms associated with Down Syndrome Regression Disorder.
• These findings highlight the need for further research to identify alternative factors contributing to regression in this population.