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March 3, 2026Frontiers in Pharmacology1 citationsOpen Access

Case Report: Toxic epidermal necrolysis induced by sintilimab in a patient with advanced lung squamous cell carcinoma

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JWJiaxing WuMHMingjun HuJCJ. Chen

Key Points

  • Toxic epidermal necrolysis developed following sintilimab administration in one patient.
  • Monitoring for skin reactions is critical during immune checkpoint inhibitor therapy.
  • Case emphasizes the serious risks in advanced lung squamous cell carcinoma treatment with sintilimab.
  • Immediate intervention may be necessary to address severe adverse effects associated with therapy.

Abstract

This report highlights the potential for Sintilimab to induce life-threatening TEN, emphasizing the need for vigilant monitoring and prompt intervention during ICIs therapy.

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Cite This Study

Wu et al. (2026) studied this question.

synapsesocial.com/papers/69a75e05c6e9836116a285ddhttps://doi.org/10.3389/fphar.2026.1610305
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