Catecholaminergic storm and extreme blood pressure lability induced by combined levodopa/benserazide, selegiline, and piribedil in Parkinson’s disease: a case report

Key Points

• Extreme blood pressure lability was observed following the combination of levodopa, benserazide, selegiline, and piribedil.
• A 65-year-old male with Parkinson’s experienced significant blood pressure changes when treated with these medications.
• Treatment included combined administration of levodopa, benserazide, selegiline, and piribedil, which led to abnormal physiological responses.
• Highlights the potential risks associated with polypharmacy in Parkinson’s disease management; further investigation needed.