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March 3, 2026Journal of the Neurological Sciences

Hyperintense basal ganglia on T1-MRI in two patients with elevated serum manganese due to cirrhosis

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Authors

ATAhmet Tüfekçi

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Overview

Case observations report hyperintense basal ganglia on T1-MRI in patients with cirrhosis, suggesting a link to manganese accumulation.

Key Points

  • Hyperintense basal ganglia were observed on T1-MRI scans, indicating a potential link to manganese.
  • Two patients exhibited elevated serum manganese levels, contributing to MRI findings of brain changes.
  • MRI analysis showed that abnormal manganese levels correlated with changes in the basal ganglia.
  • Findings highlight the need for further investigation into manganese's role in brain pathology during cirrhosis.

Cite This Study

Ahmet Tüfekçi (2025) studied this question.

synapsesocial.com/papers/69a75f95c6e9836116a2b0d3https://doi.org/10.1016/j.jns.2025.124963
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