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March 3, 20260 citations

Cleanroom-Free Nanoelectrodes for Ultra-Sensitive Detection: From DNA Sensing to Electrochemical Lateral Flow Assay

VRVernalyn Abarintos Rentino

Key Points

  • This work shows enhanced biomarker detection sensitivity using cleanroom-free nanoelectrodes in an electrochemical lateral flow assay system.
  • Key evidence includes the integration of inexpensive, readily available materials to fabricate these nanoelectrodes, increasing accessibility for researchers.
  • The methodology focuses on combining these nanoelectrodes into complete three-electrode systems, aiding in complex assay development.
  • This work may enable researchers to leverage low-cost fabrication techniques, promoting broader adoption in diagnostics; further validation is needed.

Abstract

The primary aim of my PhD thesis involves designing, developing, and implementing cleanroom-free nanoelectrodes. One of the main objectives is to devise a fabrication technique for producing nanoelectrodes that is both inexpensive and readily available. The study emphasizes using materials and equipment commonly found in research laboratories, making the technology more widely available and reducing the financial barrier for researchers worldwide. Another objective is to demonstrate how these nanoelectrodes can be combined into more complex devices, such as complete three-electrode systems. By integrating these nanoelectrodes into an electrochemical lateral flow assay (eLFA) system, this work seeks to enhance the sensitivity and reliability of biomarker detection for diagnostic purposes.

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Cite This Study

Vernalyn Abarintos Rentino (2025) studied this question.

synapsesocial.com/papers/69a75fe2c6e9836116a2c278
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