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March 3, 2026Pregnancy Hypertension0 citationsOpen Access

Low molecular weight heparin (LMWH) therapy guided by low placental growth factor (PlGF) in a diabetes-prevalent population: preliminary retrospective cohort

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EFErnesto A. Figueiro-FilhoGDGenevieve DietrichAPAlysa Poulin

Key Points

  • Improved glycemic control was observed with LMWH therapy in low PlGF pregnancies, which often have diabetes-related complications.
  • Findings show that lower incidences of small for gestational age (SGA) births are linked to LMWH treatment in affected populations.
  • The analysis highlights a significant relationship between placental function and the use of LMWH therapy in this context.
  • Further studies are warranted to explore biomarker-guided treatments for better pregnancy outcomes in similar populations.

Abstract

LMWH in low PlGF pregnancies, often complicated by diabetes, was associated with better glycemic control, improved placental function, and fewer SGA births. Findings support biomarker-guided trials of LMWH in thisgroup.

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Cite This Study

Figueiro-Filho et al. (2026) studied this question.

synapsesocial.com/papers/69a76030c6e9836116a2cb0ahttps://doi.org/10.1016/j.preghy.2026.101423
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