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March 3, 2026Lung Cancer0 citationsOpen Access

Incremental prognostic value of immune cell densities beyond clinical parameters in non-small cell lung cancer

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LNLove NordlingMBMax BäckmanAMArtur Mezheyeuski

Key Points

  • Immune cell densities offer limited prognostic value in predicting outcomes, indicating clinical parameters are still primary predictors.
  • Specifically, the ability of immune cell densities to enhance predictions beyond clinical parameters appears minimal.
  • Assessment of immune cell densities underscores an opportunity for development in methodology and focused analysis.
  • These findings highlight the need for improved clinical stratification strategies, as the current reliance on clinical parameters may overlook crucial data.

Abstract

Clinical parameters remain the dominant predictors of outcome in NSCLC, with immune cell densities providing only limited prognostic value for clinical stratification. The openly available code and datasets present a unique resource for method development or focused analysis.

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Cite This Study

Nordling et al. (2026) studied this question.

synapsesocial.com/papers/69a760adc6e9836116a2da86https://doi.org/10.1016/j.lungcan.2026.108935
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