Continuous, Preclinical Activity Reconstruction in 177Lu-based Radiopharmaceutical Therapy Using a Sparse Uncollimated γ-Sensor Network

Key Points

• Activity reconstruction enhances the quality and safety of 177Lu-based radiopharmaceutical therapy, targeting multiple tumors.
• The system enables high temporal resolution through frequent measurements, with improved monitoring capabilities for tumors and organs at risk.
• Assessment using a sparse uncollimated γ-sensor network shows significant advances in preclinical applications for radiation therapy.
• This approach supports further clinical adaptations, indicating important implications for patient treatment protocols and outcomes.