Target-activated genetically programmable light-up fluorescent biosensor for label-free and one-step sensing of glutathione in breast tissues

Key Points

• Glutathione detection employs a novel fluorescent biosensor for targeted sensing in tissues, enhancing diagnostic capabilities.
• The biosensor operates in a one-step process, offering an efficient method for identifying glutathione levels in breast tissues.
• Utilizing genetically programmable components, which enhance specificity and sensitivity in detecting the biomarker, indicates promising applications.
• This innovation supports advancements in non-invasive diagnostic techniques, yet further validation in clinical settings is required.