WSSV promotes its replication by inhibiting Dorsal activation via CypA in crayfish

Key Points

• WSSV promotes replication by inhibiting key immune pathways, particularly Dorsal activation.
• Key metric: inhibition of Dorsal leads to a significant increase in virus replication.
• Observational analysis of crayfish reveals the role of CypA in this inhibition process.
• These findings highlight a potential target for controlling WSSV in aquatic ecosystems, though further studies are needed.